Producing and using safe and sustainable chemicals is the most favourable strategy to avoid chemical pollution. It includes two main objectives: using safe chemicals while preventing harm to humans and the environment by avoiding substances of concern for non-essential uses, and promoting the development of safe and sustainable chemicals and materials. This covers the development of clean production processes and technologies, and innovative tools for chemicals testing and risk assessments.

Below, indicators refer to quantitative variables showing the trend or status of a phenomenon over time and occurring at the EU level. Signals can be a compilation of qualitative and/or quantitative data with limited geographical and time coverage. They provide additional insights, may indicate a trend for a specific phenomenon, that are deemed worth exploring despite incomplete coverage.